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What do we know about the antibody responses to SARS-CoV-2?
Immunobiology ( IF 2.5 ) Pub Date : 2021-01-23 , DOI: 10.1016/j.imbio.2021.152054
Francisco Alejandro Lagunas-Rangel 1 , Venice Chávez-Valencia 2
Affiliation  

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide causing a pandemic with millions of infected people and deaths. Currently, the scientific community is working hard to develop a specific vaccine or treatment. However, since antibody production is an important part of the adaptive immune response, to develop vaccines and therapies, we must understand the antibody response to SARS-CoV-2 infection. In this work, we summarize the most important findings of antibody-mediated immunity against SARS-CoV-2 and highlight its role in the efficient use of plasma from convalescent patients and the direct application of antibodies as treatment.



中文翻译:

我们对 SARS-CoV-2 的抗体反应了解多少?

严重急性呼吸综合征冠状病毒 2 (SARS-CoV-2) 已在全球范围内传播,引发大流行,导致数百万人感染和死亡。目前,科学界正在努力开发特定的疫苗或治疗方法。然而,由于抗体产生是适应性免疫反应的重要组成部分,为了开发疫苗和疗法,我们必须了解针对 SARS-CoV-2 感染的抗体反应。在这项工作中,我们总结了抗体介导的针对 SARS-CoV-2 的免疫的最重要发现,并强调了其在有效利用恢复期患者血浆以及直接应用抗体作为治疗方面的作用。

更新日期:2021-02-01
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