Meriones shawi (M.shawi) is the main reservoir host for zoonotic cutaneous leishmaniasis (ZCL) in Central Tunisia. The incorporation of environmental and climatic effects on the spread of ZCL in M. shawi remains difficult. This study presents an agent-based model (ABM) to overcome these difficulties and examine the impact of environment (i.e. vegetation cover) and climate (i.e. temperature) on M. shawi movement and prevalence. The model simulation considers two agent types: rodent agent and field unit agent. We tested the model according to two types of rodent movement: random and thoughtful. We integrated time dependent normalized difference vegetation index (NDVI) in order to test the land cover effects on rodent movement and ZCL transmission. The results confirmed that the spread of the disease depends on rodent movement. We observed that prevalence and distribution are the closest to field data when the vegetation cover is highest and that rodents go for thoughtful movement. In addition, we found that the nature of movement (random or thoughtful) and prevalence depends strongly on minimum food detection.

Meriones shawi（M.shawi）是突尼斯中部人畜共患皮肤利什曼病（ZCL）的主要宿主。尚难将环境和气候效应纳入ZCL在Shawi支原体中的传播。这项研究提出了一种基于代理的模型（ABM）来克服这些困难并研究环境（即 植被覆盖）和气候（即 温度）对沙门氏菌的影响运动和患病率。模型仿真考虑了两种媒介物类型：啮齿动物媒介物和田间单位媒介物。我们根据两种类型的啮齿动物运动对模型进行了测试：随机和周到。我们集成了时间依赖性归一化植被指数（NDVI），以测试土地覆盖对啮齿动物运动和ZCL传播的影响。结果证实该疾病的传播取决于啮齿动物的运动。我们观察到，当植被覆盖率最高且啮齿动物进行深思熟虑的运动时，患病率和分布最接近田间数据。此外，我们发现运动（随机或有思想）和患病率的性质在很大程度上取决于最少的食物检测。