The antibacterial materials are rapidly emerging as a primary component in mitigation of bacterial pathogens, and functional polymers play a vital role for the preparation of antibacterial coatings. In this study, using one-pot soap-free emulsion polymerization, we synthesized blackberry-shape cationic copolymer particles (BsCCP) with broad-spectrum antibacterial activity, and the BsCCP emulsion was added to the coating of the interior walls, which afforded BsCCP-based coating (BsCCP-C). The effects of surfactants, initiators, temperature, and monomer ratio on the synthesis of BsCCP were investigated. Besides, BsCCP was characterized by Fourier Transform infrared spectra (FT-IR), scanning electron microscope (SEM) and X-ray photoelectron spectroscopy (XPS). The antibacterial activities of BsCCP and BsCCP-C against Escherichia coli and Staphylococcus aureus were evaluated. BsCCP showed positive charge, high specific surface area and rough surface, which presented strong bactericidal activity. Its antibacterial mechanism was also discussed and demonstrated. To sum up, the BsCCP and BsCCP-C with high antibacterial activity showed great potential and was expected to be a candidate of antibacterial coating materials, which are able to use for rapidly and effectively resisting to the bacterial propagation.

抗菌材料正在迅速成为缓解细菌病原体的主要成分，功能性聚合物在抗菌涂层的制备中起着至关重要的作用。在这项研究中，我们使用一锅无皂乳液聚合法合成了具有广谱抗菌活性的黑莓形阳离子共聚物颗粒（BsCCP），并将BsCCP乳液添加到内墙涂料中，从而获得了BsCCP-基涂料（BsCCP-C）。研究了表面活性剂，引发剂，温度和单体比例对BsCCP合成的影响。此外，BsCCP的特征在于傅立叶变换红外光谱（FT-IR），扫描电子显微镜（SEM）和X射线光电子能谱（XPS）。BsCCP和BsCCP-C的抗菌活性评估了大肠杆菌和金黄色葡萄球菌。BsCCP显示出正电荷，高的比表面积和粗糙的表面，具有很强的杀菌活性。还讨论并证明了其抗菌机理。综上所述，具有高抗菌活性的BsCCP和BsCCP-C显示出巨大的潜力，并有望成为能够快速有效地抵抗细菌繁殖的抗菌包衣材料的候选者。