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Optimal Evolution of the Standard Genetic Code
Journal of Molecular Evolution ( IF 2.1 ) Pub Date : 2021-01-24 , DOI: 10.1007/s00239-020-09984-8
Michael Yarus 1
Affiliation  

The Standard Genetic Code (SGC) exists in every known organism on Earth. SGC evolution via early unique codon assignment, then later wobble, yields coding resembling the near-universal code. Below, later wobble is shown to also create an optimal route to accurate codon assignment. Time of optimal codon assignment matches the previously defined mean time for ordered coding, exhibiting ≥ 90% of SGC order. Accurate evolution is also accessible, sufficiently frequent to appear in populations of 103 to 104 codes. SGC-like coding capacity, code order, and accurate assignments therefore arise together, in one attainable evolutionary intermediate. Examples, which plausibly resemble coding at evolutionary domain separation, are characterized.



中文翻译:

标准遗传密码的优化进化

标准遗传密码 (SGC) 存在于地球上每个已知的生物体中。SGC 通过早期独特的密码子分配进化,然后是摆动,产生类似于近乎通用代码的编码。下面,显示了后来的摆动也创建了准确密码子分配的最佳途径。最佳密码子分配时间与之前定义的有序编码平均时间相匹配,表现出 ≥ 90% 的 SGC 顺序。准确的进化也是可以访问的,足够频繁地出现在 10 3到 10 4代码的群体中。因此,在一个可实现的进化中间体中,类似于 SGC 的编码能力、代码顺序和准确分配一起出现。特征似乎类似于进化域分离中的编码的示例。

更新日期:2021-01-24
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