Nanoscaled zinc oxide (ZnO) was synthesized via a benign mineralization reaction using mono-amino acid as templates. Characterized by Fourier transform infrared spectroscopy, X-ray diffraction, and scanning electron microscopy, it was found that the microstructure of as-prepared ZnO can be fine-tuned into olive-like and flake-like structures with leucine and histidine respectively. Otherwise, the photoluminescence (PL) results indicate that biomineralized ZnO nanoparticles show a potential application in the fields of optical devices. To further explore the biological performance of as-prepared ZnO nanoparticles, antibacterial activity tests against Staphylococcus aureus and Escherichia coli, and cytocompatibility on mouse MC3T3 cells were also investigated. The superior biological properties of these biomineralized ZnO together with their intrinsic photoluminescent properties open perspectives for the development of biomedical applications.

以单氨基酸为模板，通过良性矿化反应合成了纳米级氧化锌（ZnO）。通过傅里叶变换红外光谱，X射线衍射和扫描电子显微镜进行表征，发现所制备的ZnO的微结构可以分别用亮氨酸和组氨酸微调成橄榄状和片状结构。否则，光致发光（PL）结果表明生物矿化的ZnO纳米颗粒在光学器件领域显示出潜在的应用。为了进一步探索制备的ZnO纳米粒子的生物学性能，对金黄色葡萄球菌和大肠杆菌的抗菌活性测试，还研究了小鼠MC3T3细胞的细胞相容性。这些生物矿化的ZnO的优越的生物学特性及其固有的光致发光特性为生物医学应用的发展开辟了前景。