Background: The most common way to validate a pneumatic tube system (PTS) is to compare PTS transported blood samples to blood samples carried by hand. The importance of also measuring the forces inside the PTS has been emphasized. The aim of this study was to define a validation protocol using a mini data logger (VitalVial, Motryx Inc., Canada) to reduce the need for donor samples in PTS validation.

Methods: As an indicator of the total vibration the blood samples are exposed to under PTS transportation, the area under the curve (AUC) was determined by a VitalVial for all hospital Tempus600 lines using a five-day validation protocol. Only the three lines with the highest AUC were clinically validated by analyzing potassium, lactate dehydrogenase (LDH) and aspartate aminotransferase (AST). A month after PTS commissioning, a follow-up on laboratory data was performed.

Results: Mean AUC of the six lines ranged between 347 and 581. The variability of the AUC was between 1.51-11.55%. In the laboratory data follow-up, an increase in LDH hemolysis was seen from the three lines with the highest AUC and the emergency department which was not detected in the clinical validation. When the Tempus600 system was in commission, a higher mean AUC was measured.

Conclusion: A three-day validation protocol using VitalVials is enough to determine the stability of a Tempus600 system and can greatly reduce the need for donor samples. When in commission, the stability of the PTS should be verificated and LDH hemolysis should be routinely checked.

背景：验证气动管系统 (PTS) 的最常见方法是将 PTS 运输的血样与手工携带的血样进行比较。还强调了测量 PTS 内部力的重要性。本研究的目的是使用小型数据记录器（VitalVial，Motryx Inc.，加拿大）定义验证协议，以减少 PTS 验证中对供体样本的需求。

方法：作为血液样本在 PTS 运输下暴露于总振动的指标，曲线下面积 (AUC) 是通过 VitalVial 使用为期五天的验证方案为所有医院 Tempus600 生产线确定的。通过分析钾、乳酸脱氢酶 (LDH) 和天冬氨酸转氨酶 (AST)，只有具有最高 AUC 的三个品系得到了临床验证。在 PTS 调试一个月后，对实验室数据进行了跟踪。

结果：6 条线的平均 AUC 范围在 347 和 581 之间。AUC 的变异性在 1.51-11.55% 之间。在实验室数据随访中，AUC最高的3条线和临床验证未检测到的急诊科均出现LDH溶血增加。当 Tempus600 系统投入使用时，测得的平均 AUC 更高。

结论：使用 VitalVials 的三天验证方案足以确定 Tempus600 系统的稳定性，并且可以大大减少对供体样本的需求。投入使用时，应验证 PTS 的稳定性，并应定期检查 LDH 溶血。