Wild animals have been implicated as the origin of SARS-CoV-2, but it is largely unknown how the virus affects most wildlife species and if wildlife could ultimately serve as a reservoir for maintaining the virus outside the human population. Here we show that several common peridomestic species, including deer mice, bushy-tailed woodrats, and striped skunks, are susceptible to infection and can shed the virus in respiratory secretions. In contrast, we demonstrate that cottontail rabbits, fox squirrels, Wyoming ground squirrels, black-tailed prairie dogs, house mice, and racoons are not susceptible to SARS-CoV-2 infection. Our work expands upon the existing knowledge base of susceptible species and provides evidence that human-wildlife interactions could result in continued transmission of SARS-CoV-2.

中文翻译：

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哺乳动物对SARS-CoV-2感染的易感性调查

野生动物被认为是SARS-CoV-2的起源，但很大程度上未知该病毒如何影响大多数野生生物种类，以及野生生物是否最终可以作为将病毒保持在人类之外的库。在这里，我们显示了几种常见的蠕动物种，包括鹿小鼠，丛生的树尾类松鼠和条纹臭鼬，都容易感染并且可以将病毒从呼吸道分泌物中排出。相比之下，我们证明棉尾兔，狐狸松鼠，怀俄明州地松鼠，黑尾土拨鼠，家鼠和浣熊对SARS-CoV-2感染不敏感。我们的工作扩展了现有的易感物种知识库，并提供了证据，表明人与野生生物的相互作用可能导致SARS-CoV-2继续传播。