A new method is presented for full-field optical coherence tomography imaging, which permits capturing single shot phase sensitive imaging through simultaneous acquisition of four phase-shifted images with a single camera using unpolarized light for object illumination. Our method retains the full dynamic range of the camera by using different areas of a single camera sensor to capture each image. We demonstrate the performance of our method by imaging phantoms and live cultures of fibroblast, cancer, and macrophage cells to achieve 59 dB sensitivity with isotropic resolution down to 1 μm, and displacement sensitivity down to 0.1 nm. Our method can serve as a platform for developing high resolution imaging systems because when used in conjunction with broadband spatially incoherent light sources, the resolution is not affected by optical aberrations or speckle noise.

中文翻译：

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同时 4 相移全视场光学相干显微镜


提出了一种用于全视场光学相干断层扫描成像的新方法，该方法允许通过使用非偏振光进行物体照明的单个相机同时采集四个相移图像来捕获单次相敏成像。我们的方法通过使用单个相机传感器的不同区域来捕获每个图像，从而保留了相机的完整动态范围。我们通过对成纤维细胞、癌症和巨噬细胞的体模和活体培养物进行成像来展示我们的方法的性能，以实现 59 dB 的灵敏度，各向同性分辨率低至 1 μm，位移灵敏度低至 0.1 nm。我们的方法可以作为开发高分辨率成像系统的平台，因为当与宽带空间非相干光源结合使用时，分辨率不受光学像差或散斑噪声的影响。