Nonlinear Analysis: Real World Applications ( IF 2 ) Pub Date : 2021-01-22 , DOI: 10.1016/j.nonrwa.2021.103290 Wenhua He , Ruixiang Xing
We study a free boundary problem modeling tumor growth with a T-periodic supply of external nutrients. The model contains two parameters and . We first show that (i) zero radially symmetric solution is globally stable if and only if ; (ii) If , then there exists a unique radially symmetric positive solution with period and it is a global attractor of all positive radially symmetric solutions for all . These results are a perfect answer to open problems in Bai and Xu [Pac. J. Appl. Math. 2013(5), 217–223]. Then, considering non-radially symmetric perturbations, we prove that there exists a constant such that is linearly stable for and linearly unstable for .
中文翻译:
自由边界问题的周期解的存在性和线性稳定性,该问题模拟了具有周期性外部营养的肿瘤生长
我们研究了使用T周期供应模拟肿瘤生长的自由边界问题 外部营养。该模型包含两个参数 和 。我们首先证明(i)当且仅当零径向对称解是全局稳定的; (ii)如果,则存在唯一的径向对称正解 随着时期 它是所有正径向对称解的全球吸引者 。这些结果是对Bai和Xu中未解决问题的完美答案。J.应用 数学。2013(5),217-223]。然后,考虑到非径向对称扰动,我们证明存在一个常数 这样 对...线性稳定 并且线性不稳定 。