Chitosan has generated enormous interest in the scientific community because of its distinctive biological and physicochemical properties, which allow new advanced structures and applications. Porous chitosan scaffolds have been extensively studied and explored in bone generation, however it is still a challenge to obtain bioabsorbable orthopedic implants that involves pure 3D dense chitosan geometries due to the inherent difficulties in producing and shaping such structures.

In this work, chitosan was blended with 10% glycerol and 10% glycerol + 10% biphasic mixture of calcium phosphate (70% hydroxyapatite with 30% β-tricalcium phosphate) to produce dense chitosan-based blocks, which were then shaped into rods. The introduction of plasticizer aimed to improve the materials ductility while the ceramic particles were used to increase stiffness and strength. The mechanical behavior of the two chitosan-based compositions was evaluated by uniaxial compression tests using a customized split-Hopkinson pressure bar (SHPB). The specimens were analysed in quasi-static conditions (less than 0.1 $s^{-1}$) and medium strain rate conditions (200–800 $s^{-1}$), both in dry state and in different hydrated conditions, in the latter case to approximate the in vivo implant conditions.

The results showed promising results for the intended application. The chitosan blends present excellent ductility with an elastic perfect-plastic behavior in quasi-static conditions, with yield stresses around 40 MPa for the dry state, with a decay for 3 MPa after 48h hydration. An empirical model was proposed to describe the flow stress curves, with a good agreement with the experimental data, allowing future modelling of this material behavior.

壳聚糖因其独特的生物学和物理化学特性而在科学界引起了极大的兴趣，这些特性允许新的先进结构和应用。多孔壳聚糖支架已经在骨生成中进行了广泛的研究和探索，但是由于在生产和成形此类结构方面存在固有的困难，因此获得具有纯3D致密壳聚糖几何形状的可生物吸收的骨科植入物仍然是一个挑战。

在这项工作中，将脱乙酰壳多糖与10％甘油和10％甘油+ 10％磷酸钙的双相混合物（70％羟基磷灰石与30％β-三钙磷酸酯）混合，制成致密的壳聚糖基嵌段，然后将其成型为棒状。增塑剂的引入旨在提高材料的延展性，而陶瓷颗粒则用于增加刚度和强度。两种壳聚糖基组合物的机械性能通过使用定制的分体式霍普金森压杆（SHPB）的单轴压缩测试进行了评估。在准静态条件下（小于0.1$s^{-\mathrm{1个}}$）和中等应变率条件（200–800 $s^{-\mathrm{1个}}$），无论是在干燥状态下还是在不同水合条件下，在后一种情况下都近似于体内植入条件。

结果显示了预期应用的良好结果。壳聚糖共混物在准静态条件下具有出色的延展性和弹性的完美塑性，在干燥状态下的屈服应力约为40 MPa，在水合48小时后的衰变应力为3 MPa。提出了一个描述流动应力曲线的经验模型，该模型与实验数据吻合得很好，从而可以对该材料行为进行将来的建模。