The sheer paucity of scientific documentation of herpetofauna in Vietnam and the rudimentary healthcare response to snakebite have stimulated this review. Over six decades of data culled from public data bases and search engines, have been used to assess snakebite burdens, clinical features of envenomation, and strategies for snakebite management in Vietnam. In addition, biochemical and proteomic analyses to decipher venom composition, rapid analytical techniques to be used for clinical diagnosis of snakebite in Vietnam have been discussed in detail. The assessment of efficacy, safety, and quality of commercial antivenom produced in Vietnam and improvement of antivenom production to meet the national requirement has been critically examined. It is apparent that snake bite incidence in Vietnam is exacerbated by mismatch in demand and supply of antivenom therapy, insufficient medical facilities, preference for traditional healers and poor management of clinical records. The impediments arising from geographical and species-specific variation in venom composition can be overcome by the ‘Omics approach’, and scientific documentation of pathophysiological manifestations post envenomation. The development of next generation of therapeutics, encouraging clinical research, novel approaches and social awareness against snakebite and its treatments have been suggested to significantly reduce the snakebite mortality and morbidity in this region.

越南关于Herpetofauna的科学文献十分匮乏，而且对蛇咬的基本医疗保健反应也激发了这一评论。从公共数据库和搜索引擎收集的六十年来的数据已用于评估蛇咬的负担，毒液的临床特征以及越南的蛇咬管理策略。此外，还详细讨论了用于解密毒液成分的生化和蛋白质组分析，以及用于越南蛇咬伤临床诊断的快速分析技术。严格审查了对越南生产的商业抗蛇毒草的功效，安全性和质量的评估，以及为满足国家要求而改进抗蛇毒草素的产量的评估。显然，由于抗蛇毒疗法的供需不匹配，医疗设施不足，对传统治疗师的偏爱以及临床记录管理不善，加剧了越南的蛇咬事件。可以通过“组学方法”和毒化后病理生理表现的科学文献来克服由毒液成分的地理和特定物种变化引起的障碍。下一代疗法的发展，令人鼓舞的临床研究，新颖的方法以及对蛇咬伤及其治疗方法的社会认识已被建议大大降低该地区的蛇咬伤死亡率和发病率。可以通过“组学方法”和毒化后病理生理表现的科学文献来克服由毒液成分的地理和特定物种变化引起的障碍。下一代疗法的发展，令人鼓舞的临床研究，新颖的方法以及对蛇咬伤及其治疗方法的社会认识已被建议大大降低该地区的蛇咬伤死亡率和发病率。可以通过“组学方法”和毒化后病理生理表现的科学文献来克服由毒液成分的地理和特定物种变化引起的障碍。下一代疗法的发展，令人鼓舞的临床研究，新颖的方法以及对蛇咬伤及其治疗方法的社会认识已被建议显着降低该地区的蛇咬伤死亡率和发病率。