Background: Neoplasms from the ventricular system share a common location but have highly variable histogenesis. Many are slowly growing tumors that behave in a benign fashion. They can be classified as primary and secondary tumors. The most common primary tumors are ependymomas, subependymomas, subependymal giant cell astrocytomas, central neurocytomas, choroid plexus tumors, meningiomas, germinomas, pineal parenchymal tumors, papillary tumors of the pineal region, chordoid gliomas, rosette-forming glioneuronal tumors of the fourth ventricle, and craniopharyngiomas. Pilocytic astrocytomas, medulloblastomas, and atypical teratoid/rhabdoid tumors often show secondary involvement of the ventricular system. Summary: Advances in neurosurgery have facilitated access to the ventricular system increasing the number of cases in which such tumors can be biopsied. In this context, cytology has been proven to be an extremely useful diagnostic tool during intraoperative pathologic consultations. Many ventricular tumors are infrequent, and the cytologic information available is limited. In this review, we describe the cytologic features of the uncommon ventricular tumors and report on unusual findings of the more common ones. For the cytologic evaluation of brain tumors, many neuropathologists prefer formalin fixation and hematoxylin and eosin staining. In this review, we highlight the cytologic findings as seen with Diff-Quik, a very popular staining method among cytopathologists. In fact, when pathologists are unfamiliar with cytology, it is common to request the assistance of cytopathologists during the evaluation of intraoperative procedures. Key Message: Ventricular tumors of the central nervous system comprise a group of heterogeneous tumors with very different cytologic features. The cytomorphology of these tumors, including rare entities, is often very characteristic, allowing a precise recognition during intraoperative pathologic consultations. Diff-Quik is a valuable staining method that can be used alone or as a complement to hematoxylin and eosin staining. Diff-Quik allows for clear visualization of the overall architecture, cytoplasmic details, and extracellular material.
Acta Cytologica

中文翻译：

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中枢神经系统室性肿瘤的细胞学特征：强调弥散快速染色涂片的审查。

背景：来自心室系统的肿瘤具有相同的位置，但具有高度可变的组织发生。许多以良性方式表现的缓慢生长的肿瘤。它们可以分为原发性和继发性肿瘤。最常见的原发性肿瘤是室管膜瘤，室管膜下瘤，室管膜下巨细胞星形细胞瘤，中枢神经细胞瘤，脉络丛肿瘤，脑膜瘤，生殖细胞瘤，松果体实质性肿瘤，松果体区域的乳头状瘤，软骨样神经胶质瘤，形成玫瑰花结的胶质神经胶质瘤和颅咽管瘤。上叶星形细胞瘤，髓母细胞瘤和不典型的类畸形/类人瘤通常表现为继发于心室系统。概要：神经外科的进步促进了进入心室系统的便利，增加了可以对此类肿瘤进行活检的病例数。在这种情况下，细胞学已被证明是术中病理咨询期间极为有用的诊断工具。许多心室肿瘤不常见，并且可用的细胞学信息有限。在这篇综述中，我们描述了罕见的心室肿瘤的细胞学特征，并报告了较常见的心室肿瘤的异常发现。对于脑肿瘤的细胞学评估，许多神经病理学家更喜欢使用福尔马林固定以及苏木精和曙红染色。在这篇综述中，我们着重介绍了Diff-Quik所见的细胞学发现，Diff-Quik是细胞病理学家中一种非常流行的染色方法。实际上，当病理学家不熟悉细胞学时，关键信息：中枢神经系统的室性肿瘤包括一组异质性肿瘤，具有非常不同的细胞学特征。这些肿瘤的细胞形态学（包括罕见实体）通常具有很高的特征，可以在术中病理会诊期间进行精确识别。Diff-Quik是一种有价值的染色方法，可以单独使用，也可以作为苏木精和曙红染色的补充。Diff-Quik可以使整体结构，细胞质细节和细胞外物质清晰可见。
细胞学学报