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Degradable tough chitosan dressing for skin wound recovery
Nanotechnology Reviews ( IF 6.1 ) Pub Date : 2020-12-31 , DOI: 10.1515/ntrev-2020-0105
Yan Kong 1 , Xiaoxuan Tang 2 , Yahong Zhao 2 , Xiaoli Chen 2 , Ke Yao 2 , Liling Zhang 2 , Qi Han 2 , Luzhong Zhang 2 , Jue Ling 2 , Yongjun Wang 2 , Yumin Yang 1, 2
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Abstract The performance of wound dressing determines the effect of wound closure and recovery. Water absorption and bacteriostasis of wound dressings play an important role in wound recovery and healing. In this study, an optimized chitosan wound dressing-tough chitosan dressing (TCS) with high water absorption, high bacteriostasis, and degradability was developed. The chemical structure of chitosan remained stable during the process of optimized treatment, and an increase in mechanical properties was obtained for the dressing. After optimization, the water absorption and antibacterial properties of the chitosan dressing were greatly improved, which is significantly better than sodium alginate dressing. The authors believe that TCS dressing with high hygroscopicity and high bacteriostasis has great potential application value in the field of wound recovery and healing.

中文翻译:

用于皮肤伤口恢复的可降解坚韧壳聚糖敷料

摘要 伤口敷料的性能决定了伤口闭合和恢复的效果。伤口敷料的吸水性和抑菌性在伤口恢复和愈合中起着重要作用。本研究开发了一种具有高吸水性、高抑菌性和可降解性的优化壳聚糖伤口敷料——坚韧壳聚糖敷料(TCS)。在优化处理过程中壳聚糖的化学结构保持稳定,敷料的力学性能得到提高。经过优化,壳聚糖敷料的吸水率和抗菌性能有了很大的提高,明显优于海藻酸钠敷料。
更新日期:2020-12-31
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