The aim of this meta-analysis was to assess the effects of a lifestyle intervention through health education on nutrition, physical activity, and healthy habits on physical and mental health-related quality of life (HRQoL), in adults with metabolic syndrome (MetS). The databases used were PubMed, WOS, and Scopus. The inclusion criteria were: observational, longitudinal and randomized clinical trial (RCT) study designs, adults (both sexes), with at least two criteria of MetS, lifestyle intervention and comparison with a control group, and a measurement of HRQoL with a validated questionnaire. We analyzed the Hedges’ g and SF-36 score. I² statistics were calculated and possible publication and small study biases were assessed using Egger’s test and funnel plots. Seven RCTs were selected for meta-analysis, based on 637 study participants. Significant improvements were found in the physical dimensions of the HRQoL scores for subjects in the active intervention compared to the group that received general lifestyle information (Hedges’ g 0.61, 95% confidence interval (CI) = 0.31–0.91). Mental health-related quality of life was also significantly improved in the intervention group compared with the control group (Hedges’ g 0.84, 95% CI = 0.64–1.03). In conclusion, our results suggest that, according to the RCTs selected for this meta-analysis, a lifestyle intervention significantly improves HRQoL in all its domains.

中文翻译：

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生活方式干预对代谢综合征成人健康相关生活质量的影响：一项荟萃分析

这项荟萃分析的目的是评估通过健康教育对患有代谢综合症（MetS）的成年人的营养，身体活动和健康习惯对身心健康相关生活质量（HRQoL）的生活方式干预的影响。使用的数据库是PubMed，WOS和Scopus。纳入标准为：观察性，纵向和随机临床试验（RCT）研究设计，成人（男女），至少具有MetS的两个标准，生活方式干预和与对照组的比较，以及经过验证的问卷对HRQoL的测量。我们分析了树篱的g和SF-36得分。我²计算统计数据并可能发表，并使用Egger检验和漏斗图评估较小的研究偏倚。基于637名研究参与者，选择了7个RCT用于荟萃分析。与接受一般生活方式信息的组相比，积极干预组受试者的HRQoL得分的身体维度有显着改善（Hedges's g为0.61，95％置信区间（CI）= 0.31-0.91）。与对照组相比，干预组的心理健康相关生活质量也得到了显着改善（Hedges's g为0.84，95％CI = 0.64–1.03）。总之，我们的结果表明，根据用于该荟萃分析的RCT，生活方式干预可在所有领域显着改善HRQoL。