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Cross‐Coupling Reactions of Aryl Halides with Primary and Secondary Aliphatic Alcohols Catalyzed by an O,N,N‐Coordinated Nickel Complex
Advanced Synthesis & Catalysis ( IF 5.4 ) Pub Date : 2021-01-21 , DOI: 10.1002/adsc.202001346
Toru Hashimoto 1 , Keisuke Shiota 1 , Kei Funatsu 1 , Yoshitaka Yamaguchi 1
Affiliation  

A synthesis of alkyl aryl ethers was achieved via the cross‐coupling of aryl halides with primary and secondary aliphatic alcohols catalyzed by a bench‐stable nickel complex supported by a monoanionic O,N,N‐tridentate ligand. This nickel‐catalyzed reaction proceeds smoothly in the absence of a phosphine ligand, affording alkyl aryl ethers in moderate to good yields.

中文翻译:

O,N,N配位的镍配合物催化卤代芳烃与脂肪族伯醇和仲醇的交叉偶联反应

烷基芳基醚的合成是通过芳基卤稳定的镍络合物(由单阴离子ONN三齿配体支撑)催化芳基卤化物与伯和仲脂族醇的交叉偶联而实现的。在没有膦配体的情况下,这种镍催化的反应平稳进行,从而以中等至良好的收率提供了烷基芳基醚。
更新日期:2021-03-16
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