We assessed maternal and infant cytomegalovirus (CMV) infection in Colombia. Maternal serum was tested for CMV immunoglobulin G antibodies at a median of 10 (interquartile range: 8–12) weeks gestation (n = 1501). CMV DNA polymerase chain reaction was performed on infant urine to diagnose congenital (≤21 days of life) and postnatal (>21 days) infection. Maternal CMV seroprevalence was 98.1% (95% confidence interval [CI]: 97.5%–98.8%). Congenital CMV prevalence was 8.4 (95% CI: 3.9%–18.3%; 6/711) per 1000 live births. Among 472 infants without confirmed congenital CMV infection subsequently tested at age 6 months, 258 (54.7%, 95% CI: 50.2%–59.1%) had postnatal infection.

中文翻译：

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哥伦比亚母婴巨细胞病毒感染流行病学

我们评估了哥伦比亚的母婴巨细胞病毒 (CMV) 感染情况。在妊娠 10 周（四分位距：8-12）周（n  = 1501）时检测母体血清中的 CMV 免疫球蛋白 G 抗体。对婴儿尿液进行 CMV DNA 聚合酶链反应以诊断先天性（≤21 天）和产后（>21 天）感染。产妇 CMV 血清阳性率为 98.1%（95% 置信区间 [CI]：97.5%–98.8%）。先天性 CMV 患病率为 8.4（95% CI：3.9%–18.3%；6/711）/1000 名活产。在 472 名未确诊先天性 CMV 感染的婴儿中，随后在 6 个月大时进行了检测，其中 258 名（54.7%，95% CI：50.2%–59.1%）发生了产后感染。