An effective electrochemical immunosensor for detecting the liver cancer biomarker was developed based on the hedgehog-like Bi₂S₃ nanostructure, which was synthesized using novel CTAB-trimellitic acid as a composite soft template and thiourea as the sulfur source by a simple hydrothermal method with 20-fold sensitivity enhancement and one order of magnitude increase of linear range. The electrochemical immunosensor presented excellent performance, and could be applied to detect the cancer biomarker in clinical serum samples.

中文翻译：

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像刺猬一样的Bi2S3纳米结构：肝癌生物标志物的合成和灵敏电化学免疫测定的新型复合软模板途径

基于刺猬样Bi ₂ S ₃纳米结构，开发了一种有效的检测肝癌生物标志物的电化学免疫传感器。该纳米结构采用新型CTAB-偏苯三酸为复合软模板，硫脲为硫源，通过简单的水热法合成。灵敏度提高了20倍，线性范围提高了一个数量级。电化学免疫传感器具有优异的性能，可用于检测临床血清样品中的癌症生物标志物。