Highly regioselective palladium-catalyzed domino reaction for post-functionalization of BODIPY,Chemical Communications

当前位置： X-MOL 学术 › Chem. Commun. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Highly regioselective palladium-catalyzed domino reaction for post-functionalization of BODIPY
Chemical Communications ( IF 4.3 ) Pub Date : 2021-1-4 , DOI: 10.1039/d0cc08163a
Sisi Wang _{1,

2,

3,

4,

5} , Zhaoli Wang _{1,

2,

3,

4,

5} , Hu Gao _{1,

2,

3,

4,

5} , Liang Jiang _{1,

2,

3,

4,

5} , Hui Liu _{1,

2,

3,

4,

5} , Fan Wu _{1,

2,

3,

4,

5} , Yue Zhao _{1,

2,

3,

4,

5} , Kin Shing Chan _{1,

2,

3,

4,

5} , Zhen Shen _{1,

2,

3,

4,

5}

Affiliation

A series of benzo[a]-fused BODIPYs and the corresponding isomeric naphthyl-BODIPYs have been synthesized through a facile one-pot palladium-catalyzed domino reaction of BODIPY precursors (2-bromo-BODIPYs) with diarylethynes, via “cis, cis” and “trans, cis” addition transition states with alkynes, respectively. This reaction exhibits unprecedentedly complete cyclization regioselectivity to the a-position of the BODIPY over the b-one, and the resulting products can be effectively regulated by the substituent choice on the diarylethynes.

中文翻译：

高度区域选择性的钯催化的多米诺骨牌反应，用于BODIPY的后功能化

通过BODIPY前体（2-溴-BODIPYs）与二芳基乙炔的简单的一锅钯催化多米诺反应，通过“顺式，顺式”合成了一系列的苯并[ a ]稠合的BODIPY和相应的异构萘基-BODIPY。和“反式，顺式”分别与炔烃的加成过渡态。该反应对BODIPY的b位上的BODIPY的a位表现出前所未有的完全环化区域选择性，并且可以通过在二芳基乙炔上选择取代基来有效调节所得产物。

更新日期：2021-01-20

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11