A novel and mild Cu-catalyzed oxidative dual arylation of carbon–carbon double bonds in acrylamides with 3-aminoindazoles is proposed for the synthesis of cyanoarylated oxindoles. Notably, 3-aminoindazoles are employed as efficient arylating agents via the cleavage of two C–N bonds. This oxidative dual arylation of active alkenes involves a radical process and undergoes a sequence of 3-aminoindazole oxidation, two-C–N-bond cleavage, cyanoaryl radical addition, and intramolecular cyclization.

中文翻译：

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铜催化活性烯烃的氧化双芳基化：通过3-氨基吲唑脱氮制备氰基芳基化吲哚

提出了一种新颖且温和的铜催化丙烯酰胺中的碳-碳双键与3-氨基吲唑的氧化双芳基化反应，用于氰基芳基化吲哚的合成。值得注意的是，通过切割两个C–N键可以将3-氨基吲唑用作有效的芳基化剂。活性烯烃的这种氧化性双芳基化涉及一个自由基过程，并经历了一系列的3-氨基吲唑氧化，两个C-N键裂解，氰基芳基自由基加成和分子内环化的过程。