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Point-of-Care Diagnoses and Assays Based on Lateral Flow Test
International Journal of Analytical Chemistry ( IF 1.5 ) Pub Date : 2021-01-20 , DOI: 10.1155/2021/6685619
Miroslav Pohanka 1
Affiliation  

Analytical devices for point-of-care diagnoses are highly desired and would improve quality of life when first diagnoses are made early and pathologies are recognized soon. Lateral flow tests (LFTs) are such tools that can be easily performed without specific equipment, skills, or experiences. This review is focused on the use of LFT in point-of-care diagnoses. The principle of the assay is explained, and new materials like nanoparticles for labeling, new recognition molecules for interaction with an analyte, and new additional instrumentation like signal scaling by a smartphone camera are described and discussed. Advantages of the LFT devices as well as their limitations are described and discussed here considering actual papers that are properly cited.

中文翻译:

基于侧向流动测试的即时诊断和分析

急切需要用于现场诊断的分析设备,这种分析设备可以及早诊断并尽快识别出病状,从而改善生活质量。横向流量测试(LFT)是无需特定设备,技能或经验即可轻松执行的工具。这篇综述的重点是在现场诊断中使用LFT。解释了测定的原理,并描述并讨论了新材料,例如用于标记的纳米颗粒,新的与分析物相互作用的识别分子,以及新的其他仪器,例如智能手机相机的信号缩放。LFT设备的优点及其局限性在此处进行了描述和讨论,同时考虑了被正确引用的实际论文。
更新日期:2021-01-20
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