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ECG Markers of Cardiovascular Toxicity in Adult and Pediatric Cancer Treatment
Disease Markers Pub Date : 2021-01-19 , DOI: 10.1155/2021/6653971
Ștefan Spînu 1, 2 , Gabriel Cismaru 3 , Paul-Mihai Boarescu 4 , Sabina Istratoaie 5 , Alina Gabriela Negru 6 , Cecilia Lazea 7 , Simona Sorana Căinap 8 , Daniela Iacob 9 , Alin Ionut Grosu 10 , George Saraci 11 , Claudia Burz 1, 12 , Andrei Cosmin Cismaru 12, 13
Affiliation  

When a cardiologist is asked to evaluate the cardiac toxic effects of chemotherapy, he/she can use several tools: ECG, echocardiography, coronary angiography, ventriculography, and cardiac MRI. Of all these, the fastest and easiest to use is the ECG, which can provide information on the occurrence of cardiac toxic effects and can show early signs of subclinical cardiac damage. These warning signs are the most desired to be recognized by the cardiologist, because the dose of chemotherapeutics can be adjusted so that the clinical side effects do not occur, or the therapy can be stopped in time, before irreversible side effects. This review addresses the problem of early detection of cardiotoxicity in adult and pediatric cancer treatment, by using simple ECG recordings.

中文翻译:

成人和儿童癌症治疗中心血管毒性的心电图标志物

当心脏病专家被要求评估化疗的心脏毒性作用时,他/她可以使用多种工具:心电图、超声心动图、冠状动脉造影、心室造影和心脏 MRI。在所有这些中,最快和最容易使用的是心电图,它可以提供有关心脏毒性作用发生的信息,并可以显示亚临床心脏损伤的早期迹象。这些警告信号是心脏病专家最希望识别的,因为可以调整化疗药物的剂量,这样就不会出现临床副作用,或者可以在出现不可逆副作用之前及时停止治疗。本综述通过使用简单的心电图记录解决了在成人和儿童癌症治疗中早期发现心脏毒性的问题。
更新日期:2021-01-20
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