89 Sr is used in bone pain palliative care of cancer patients and the same is being produced presently via the 89 Y(n, p) 89 Sr reaction by irradiating yttria target in Fast Breeder Test Reactor (FBTR). An efficient separation method was standardized for the removal of bulk yttrium target by extraction chromatography using di(2-ethylhexyl) phosphoric acid (HDEHP) impregnated on XAD-7 resin. In the present paper, the extraction behavior of Sr(II) and Y(III) was studied as a function of the concentration of nitric acid in the aqueous phase and concentration of HDEHP in the resin phase. The separation of Sr(II) and Y(III) was standardized using the above resins and the method was subsequently applied satisfactorily for the removal of yttrium from the dissolver solution of FBTR irradiated yttria pellet towards the purification of 89 Sr. A baseline separation of 89 Sr and Y was achieved. Leaching and breakthrough capacity studies were evaluated for the resins and it was established that the stability and capacity of the resins were satisfactory. The breakthrough capacity was found to be 12 mg Y(III) per gram of the HDHEP resin whereas the leaching studies established that the resins are stable for multiple cycle of operations.

中文翻译：

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HDEHP浸渍XAD-7树脂通过萃取色谱法从FBTR辐照的氧化钇靶中纯化89Sr

89 Sr用于癌症患者的骨痛姑息治疗，目前通过在快速育种反应堆（FBTR）中照射氧化钇靶标通过89 Y（n，p）89 Sr反应产生。使用浸入XAD-7树脂的二（2-乙基己基）磷酸（HDEHP）通过萃取色谱法，将一种有效的分离方法进行了标准化，以去除大量钇靶标。在本文中，研究了Sr（II）和Y（III）的萃取行为与水相中硝酸浓度和树脂相中HDEHP浓度的关系。使用上述树脂对Sr（II）和Y（III）的分离进行了标准化，随后该方法令人满意地应用于从FBTR辐照的氧化钇小球的溶解剂溶液中去除钇，以纯化89Sr。实现了89 Sr和Y的基线分离。对树脂的浸出和突破容量研究进行了评估，并确定了树脂的稳定性和容量令人满意。发现突破容量为每克HDHEP树脂12 mg Y（III），而浸出研究确定该树脂对于多个操作循环均稳定。