There is no denying the Central Dogma’s impact on the biological sciences. Since the Dogma’s formulation by Francis Crick in 1958, however, many have debated the Dogma’s empirical adequacy. My aim is to move beyond these discussions, and instead consider the Central Dogma’s significance to contemporary biological practice. To do this, I consider four distinct approaches for determining the non-descriptive methodological significance of a scientific principle. I argue that these approaches fail to vindicate the Central Dogma, and that, under many of these approaches, the Dogma amounts to a triviality.

中文翻译：

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超越描述的准确性：分子生物学在科学实践中的中心法则

不可否认，中心法则对生物科学的影响。然而，自从弗朗西斯·克里克在 1958 年提出教条以来，许多人一直在争论该教条在经验上的充分性。我的目标是超越这些讨论，转而考虑中心法则对当代生物学实践的意义。为此，我考虑了四种不同的方法来确定科学原理的非描述性方法学意义。我认为这些方法无法证明中心教条的正确性，并且在许多这些方法下，教条无足轻重。