Abstract

Objective: To determine the effectiveness of a 13-week individual reminiscence therapy (RT) intervention on cognition, memory, executive function, mood, and quality of life of people with Alzheimer’s disease and vascular dementia. Method: Non-protocolized analysis using data from a larger multicenter, single-blind, randomized, parallel two-arm RCT of RT for people with neurocognitive disorders. A sample of 148 people with probable Alzheimer’s disease or vascular dementia attending 23 Portuguese institutions providing care and support services for older adults were selected. Intervention group (n = 74) received 26 individual RT sessions, twice a week for 13 weeks. Control group (n = 74) maintained their treatment as usual. Outcomes were global cognitive function (MMSE), memory (MAT), executive function (FAB), mood (GDS-15), and self-reported quality of life (QoL-AD). All participants were assessed at baseline (T0) and 15 weeks later (T1). Results: The results showed a significant effect of the intervention on global cognition (Group X Time interaction F(1, 128) = 10.542, p = .001, η_p² = .076), memory (F(1,128) = 9.881, p = .002, η_p² = .072), and quality of life (F(1,128) = 0.181, p = .671, η_p² = .001), with medium effect sizes. A small effect on executive function (F(1,127) = 11.118, p = .001, η_p² = .080) was also found. No effects were found on depressive symptoms (F(1,128) = 0.181, p = .671, η_p² = .001). Conclusion: Individual RT may have beneficial effects on cognition and quality of life of people with Alzheimer’s disease or vascular dementia.

摘要

目的：确定为期 13 周的个体回忆疗法 (RT) 干预对阿尔茨海默病和血管性痴呆患者的认知、记忆、执行功能、情绪和生活质量的有效性。方法：非协议化分析使用来自神经认知障碍患者的 RT 的更大的多中心、单盲、随机、平行双臂 RCT 的数据。选择了在 23 家葡萄牙机构为老年人提供护理和支持服务的 148 名可能患有阿尔茨海默氏病或​​血管性痴呆症的人作为样本。干预组 (n = 74) 接受了 26 次单独的 RT 课程，每周两次，持续 13 周。对照组 (n = 74) 照常维持治疗。结果是整体认知功能 (MMSE)、记忆 (MAT)、执行功能 (FAB)、情绪 (GDS-15) 和自我报告的生活质量 (QoL-AD)。所有参与者都在基线 (T0) 和 15 周后 (T1) 进行了评估。结果：结果表明，干预对全局认知（X 组时间交互F (1, 128) = 10.542，p = .001，η _p ² = .076）、记忆（F (1,128) = 9.881，p = .002，η _p ² = .072）和生活质量（F (1,128) = 0.181，p = .671，η _p ² = .001），具有中等效应值。还发现对执行功能的影响很小（F (1,127) = 11.118，p = .001，η _p ² = .080）。没有发现对抑郁症状的影响 ( F (1,128) = 0.181,p = .671，η _p ² = .001）。结论：个体化 RT 可能对阿尔茨海默病或血管性痴呆患者的认知和生活质量产生有益影响。