Following acid perfusion, esophageal pH is restored by swallowed bicarbonate-containing saliva secreted in response to a vagal esophago-salivary reflex. At impedance-pH monitoring, the post-reflux swallow-induced peristaltic wave (PSPW) index puts into relationship timely post-reflux swallows with the number of reflux events: Low values typify reflux-related heartburn (RRH) and lack of on-therapy improvement characterizes proton pump inhibitor (PPI) failure. Considerable esophageal pH increments associated with PSPWs could demonstrate the occurrence of esophago-salivary reflex in clinical setting, while its relevance could be shown by lower esophageal pH increments in PPI-refractory RRH.

中文翻译：

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与食管反流后吞咽诱导的蠕动波相关的食管 pH 值增加表明食管-唾液反射在临床环境中的发生和相关性

酸灌注后，食道的 pH 值通过吞咽响应迷走神经食道-唾液反射而分泌的含碳酸氢盐的唾液恢复。在阻抗-pH 监测中，反流后吞咽诱发的蠕动波 (PSPW) 指数与反流事件的数量相关联：低值代表反流相关的胃灼热 (RRH) 和缺乏治疗改善表征质子泵抑制剂 (PPI) 故障。与 PSPWs 相关的相当大的食管 pH 值增加可以证明临床环境中食管-唾液反射的发生，而 PPI 难治性 RRH 中食管 pH 值增加较低可以证明其相关性。