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Enhancement of conductivity, mechanical and biological properties of polyaniline-poly(N-vinylpyrrolidone) cryogels by phytic acid
Polymer ( IF 4.1 ) Pub Date : 2021-01-20 , DOI: 10.1016/j.polymer.2021.123450
Konstantin A. Milakin , Zuzana Morávková , Udit Acharya , Martina Kašparová , Stefan Breitenbach , Oumayma Taboubi , Jiří Hodan , Jiřina Hromádková , Christoph Unterweger , Petr Humpolíček , Patrycja Bober

Polyaniline-based cryogels were prepared by oxidative cryopolymerization in the presence of various concentrations of poly(N-vinylpyrrolidone) and phytic acid used as a polymer support and a dopant, respectively. Mechanical strength and handling stability of the resulting macroporous materials (pore size up to 70 μm) were significantly improved by the addition of poly(N-vinylpyrrolidone) into the polymerization system compared to the cryogels crosslinked only by phytic acid. Increase of poly(N-vinylpyrrolidone) concentration in the reaction medium above 5 wt%, while not noticeably changing mechanical properties, was found to lead to a decrease of conductivity and specific surface area. Introduction of optimal amount of phytic acid (0.2 M) as an additional codopant, in opposite, allowed enhancement of the material conductivity and specific surface area as well as increase of their tensile modulus. Polyaniline-poly(N-vinylpyrrolidone) cryogels containing phytic acid also showed better cytocompatibility due to lower cytotoxicity and improved cell adhesion and proliferation.



中文翻译:

植酸增强聚苯胺-聚(N-乙烯基吡咯烷酮)冷冻凝胶的电导率,力学和生物学性能

在各种浓度的聚(N-乙烯基吡咯烷酮)和植酸分别用作聚合物载体和掺杂剂的情况下,通过氧化冷冻聚合制备基于聚苯胺的冷冻凝胶。与仅通过植酸交联的冷冻凝胶相比,通过向聚合体系中添加聚(N-乙烯基吡咯烷酮),可以显着提高所得大孔材料(孔径最大为70μm)的机械强度和操作稳定性。聚(N发现在反应介质中浓度超过5wt%的-乙烯基吡咯烷酮)虽然没有显着改变机械性能,但是导致电导率和比表面积的降低。相反,引入最佳量的植酸(0.2 M)作为辅助共掺杂剂,可以提高材料的电导率和比表面积,并提高其拉伸模量。含有植酸的聚苯胺-聚(N-乙烯基吡咯烷酮)冷冻凝胶由于具有较低的细胞毒性和改善的细胞黏附和增殖作用,因此也显示出更好的细胞相容性。

更新日期:2021-01-28
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