In order to maintain pregnancy rates following single embryo transfer, optimisation of embryo culture and selection is vital. Time-lapse monitoring (TLM) has the potential to play a crucial role by providing sequential images of embryo development and minimal disturbance. Therefore, in this study morphometric assessment of blastocyst area and maximum width was performed in order to evaluate if these parameters are associated with pregnancy outcomes in IVF/ICSI cycles. This is a retrospective study of 664 patients who had elective single blastocyst transfer (eSBT). The EmbryoScope drawing tools were used to measure specific variables such as the maximum blastocyst width and blastocyst area. Our results show that women who were pregnant had significantly (P < 0.01) larger blastocyst width [median (range) μm] 184 (125–239) versus non-pregnant, 160 (120–230)] and area [median (range) μm²] 26099 (12101–45,280) versus non-pregnant women, 22,251 (10992–37,931)]. A univariate logistic regression performed showed that blastocyst width [(OR = 1.026, 95% CI = (1.019, 1.033)] was significant (P < 0.01) and for every μm increase of blastocyst width, the odds of clinical pregnancy increase by 2.6%. A univariate logistic regression performed showed that blastocyst area [(OR = 1.00008, 95% CI = (1.00006, 1.00011)] was significant with P < 0.01. For every μm² increase of blastocyst area, our data showed the odds of clinical pregnancy increase by 0.008%. Hosmer-Lemeshow tests of calibrations were performed to verify calibration. Although our findings show a clear correlation between blastocyst dimensions and the clinical pregnancy rate, further studies are necessary to confirm these observations.

为了维持单胚胎移植后的妊娠率，优化胚胎培养和选择至关重要。延时监测 (TLM) 有可能通过提供胚胎发育的连续图像和最小的干扰发挥关键作用。因此，在本研究中，对囊胚面积和最大宽度进行了形态测量评估，以评估这些参数是否与 IVF/ICSI 周期中的妊娠结局相关。这是一项对 664 名选择性单囊胚移植 (eSBT) 患者的回顾性研究。EmbryoScope 绘图工具用于测量特定变量，例如最大囊胚宽度和囊胚面积。我们的结果表明，怀孕的女性有显着（P < 0.01) 更大的囊胚宽度 [中位数（范围）μm] 184 (125–239​​) 与未怀孕的 160 (120–230)] 和面积 [中位数（范围）μm ² ] 26099 (12101–45,280) 与未怀孕孕妇，22,251 (10992–37,931)]。单因素logistic回归显示囊胚宽度[(OR = 1.026, 95% CI = (1.019, 1.033)]显着( P  < 0.01)，囊胚宽度每增加μm，临床妊娠几率增加2.6% . 进行的单变量逻辑回归表明，囊胚面积 [(OR = 1.00008, 95% CI = (1.00006, 1.00011)] 具有显着性，P  < 0.01。对于每 μm ²随着囊胚面积的增加，我们的数据显示临床妊娠的几率增加了 0.008%。执行校准的 Hosmer-Lemeshow 测试以验证校准。尽管我们的研究结果表明囊胚尺寸与临床妊娠率之间存在明显的相关性，但仍需要进一步的研究来证实这些观察结果。