Five compounds including three triterpenoids and two sesquiterpenes were isolated from Alimatis rhizoma. Their chemical structures were determined to be alisol B 23-acetate (1), alisol C 23-acetate (2), alisol B (3), alismol (4) and alismoxide (5) by various spectroscopic analysis, including 1H-NMR, 13C-NMR, HMBC and MS spectra. Compounds 1–5 were evaluated for their antibacterial potential against 6 strains of bacteria including three drug-resistant bacteria (one methicillin-resistant Staphylococcus aureus strain CCARM 3506, two quinolone-resistant Staphylococcus aureus strains CCARM 3505 and CCARM 3519), two G+ bacteria (Streptococcus mutans KCTC 3289 and Staphylococcus aureus KCTC 209) and one G− bacterium (Escherichia coli KCTC 1924). Compounds 1–5 showed strong antibacterial effect against S. mutans KCTC 3289, their MIC values were 2, 64, 16, 32 and 32 μg/mL, respectively. The antibacterial activity results of compounds 1–5 against these bacteria were reported for the first time. The results indicate that Alimatis rhizoma are potential sources of new antibacterial material.

中文翻译：

---

从隔离phytoconstituents的抗菌效果Alimatis剪口

从Amatatis根中分离出五种化合物，包括三个三萜和两个倍半萜。通过各种光谱分析（包括1H-NMR），确定它们的化学结构为alisol B 23-乙酸盐（1），alisol C 23-乙酸盐（2），alisol B（3），alismol（4）和Alismoxide（5）， 13 C-NMR，HMBC和MS光谱。评估了化合物1-5对6种细菌的抗菌潜能，其中包括3种耐药菌（1种耐甲氧西林金黄色葡萄球菌CCARM 3506、2种对喹诺酮耐药的金黄色葡萄球菌CCARM 3505和CCARM 3519），两种G +细菌（变形链球菌KCTC 3289和金黄色葡萄球菌KCTC 209）和一种G-细菌（大肠杆菌KCTC 1924）。化合物1-5对变形链球菌KCTC 3289表现出较强的抗菌作用，其MIC值为2、64、16 分别为32和32μg/ mL。首次报道了化合物1-5对这些细菌的抗菌活性。结果表明，Alimatis根茎是新型抗菌材料的潜在来源。