Note: In lieu of an abstract, this is an excerpt from the first page.
Ubiquitin–proteasome and lysosome–autophagy are the two main cellular degradation systems controlling cellular homeostasis in eukaryotes. The autophagy pathway started attracting particular attention only two decades ago, after the ATG genes were discovered in yeast, and their counterparts in higher eukaryotes. Since then, a tremendous amount of autophagy-related knowledge was gained leading to deciphering its molecular mechanisms and their regulations. Notably, the significance of autophagy in the pathophysiology of human disease and aging [...]

中文翻译：

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植物自噬的进展

注意：代替摘要，这是第一页的摘录。
泛素蛋白酶体和溶酶体自噬是控制真核生物细胞稳态的两个主要细胞降解系统。自从酵母中发现了ATG基因及其在高等真核生物中的对应物后，自噬途径才引起人们的特别关注，仅在二十年前。从那时起，获得了大量与自噬相关的知识，从而破译了其分子机制及其调控。值得注意的是，自噬在人类疾病和衰老的病理生理中的重要性[...]