Phytochemistry and cardiovascular protective effects of Huang-Qi (Astragali Radix),Medicinal Research Reviews

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Phytochemistry and cardiovascular protective effects of Huang-Qi (Astragali Radix)
Medicinal Research Reviews ( IF 10.9 ) Pub Date : 2021-01-19 , DOI: 10.1002/med.21785
Hui-Fei Su ₁ , Sharpkate Shaker ₁ , Yi Kuang ₁ , Meng Zhang ₁ , Min Ye _{1,

2} , Xue Qiao ₁

Affiliation

Huang-Qi (Astragali Radix) is an herbal tonic widely used in China and many other countries. It is derived from the roots of Astragalus membranaceus and A. membranaceus var. mongholicus and shows potent cardiovascular protective effects. In this article, we comprehensively reviewed 189 small molecules isolated from the two Astragalus species and discussed the interspecies chemical differences. Moreover, we summarized the pharmacological activities and mechanisms of action of Huang-Qi and its major bioactive compounds for the treatment of cardiovascular diseases. This review covers 171 references published between February 1983 and March 2020.

更新日期：2021-01-19

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