In this present work, six new Co(II) complexes {1-6, [Co(L₃)] (1); [Co(L₂)] (2); [Co(L₁)] (3); [Co(L₂)(L₃)] (4); [Co(L₁)(L₂)] (5); [Co(L₁)(L₃)] (6)} of (E)-2-(2-hydroxy-3-methoxybenzalidene)-N⁴-methylhydrazinecarbothioamide (HL₁), (E)-2-(2-hydroxy-3-methoxybenzalidene)-hydrazinecarbothioamide (HL₂) and (E)-2-(2-hydroxy-3-methoxybenzalidene)-hydrazinecarboamide (HL₃), have been synthesized and characterized by elemental analysis, analytical and FT-IR spectral investigations. The FT-IR spectral data advocated the attachment of Co²⁺ ion to the Schiff's base ligand moiety through the azomethine nitrogen, thioketonic sulfur and phenolic-O atom. The synthesized complexes 1-6 were screened for their antibacterial activities in contradiction of on two gram-positive bacteria (Bacillus subtilis and Escherichia coli) and two gram-negative bacteria (Pseudomonas aeruginosa and Staphylococcus aureus) and also screened for their antifungal in contradiction of Aspergillus Niger and Candida Albicans. Those complexes showed reasonable to substantial inhibitory effect on tested bacteria strains, whereas they exposed an admirable inhibitory effect on tested fungal strains.

在本工作中，六个新的Co（II）络合物{ 1-6， [Co（L ₃）]（1）; [Co（L ₂）]（2）；[Co（L ₁）]（3）; [Co（L ₂）（L ₃）]（4）; [Co（L ₁）（L ₂）]（5）; （E）-2-（2-羟基-3-甲氧基苯甲叉基）-N ^4-甲基肼碳硫代酰胺（HL ₁），（E）-2-（2-）的[Co（L ₁）（L ₃）]（6）}羟基-3-甲氧基苯甲叉基）-肼甲硫代酰胺（HL ₂）和（E）-2-（2-羟基-3-甲氧基苯甲叉基）-肼基甲酰胺（HL ₃）已经合成并通过元素分析，分析和FT-IR光谱研究表征。FT-IR光谱数据主张Co ²⁺离子通过甲亚胺氮，硫代酮硫和酚O原子与席夫碱配体连接。筛选了合成的复合物1-6的抗菌活性，这与两种革兰氏阳性菌（枯草芽孢杆菌和大肠杆菌）和两种革兰氏阴性菌（铜绿假单胞菌和金黄色葡萄球菌）相反）并筛选了与黑曲霉和白色念珠菌相对的抗真菌药。这些复合物对测试的细菌菌株显示出合理至实质性的抑制作用，而它们对测试的真菌菌株则表现出令人钦佩的抑制作用。