The impacts of potentially treatable psychological parameters on quality of life are relatively unreported in adults with Facioscapulohumeral, Becker and Limb-girdle muscular dystrophy. The purpose of this study was to compare quality of life, psychological parameters, and physical function between adults with muscular dystrophy and controls, and to examine relationships among these parameters in muscular dystrophy. Twenty-one adults with muscular dystrophy (n = 7 Becker, n = 8 Facioscapulohumeral, n = 6 Limb-girdle) and ten age-matched controls participated. Outcome measures were health-related quality of life, depressive symptoms, trait anxiety, self-esteem, physical self-worth and six-minute walk distance. Quality of life scores were lower in the muscular dystrophy groups than the control (p < .05). Depressive symptoms had the greatest association with quality of life in the Mental Health domain (r= −0.89, p < .001). Depressive symptoms also had the most associations with quality of life (7 of 10 domains), followed by trait anxiety (6 of 10 domains), physical self-worth (5 of 10 domains), self-esteem (4 of 10 domains) and six-minute walk distance (3 of 10 domains). Psychological parameters and, to a lesser extent, physical function impact quality of life in muscular dystrophy. This study provides a rationale to include psychological assessment and treatment within muscular dystrophy healthcare.

在患有面肩肱型、贝克尔和肢带型肌营养不良症的成年人中，潜在可治疗的心理参数对生活质量的影响相对较少。本研究的目的是比较肌肉萎缩症成人和对照组的生活质量、心理参数和身体功能，并检查肌肉萎缩症中这些参数之间的关系。21 名患有肌营养不良症的成年人（n  = 7 Becker，n  = 8 Facioscapulohumeral，n = 6 肢带）和十个年龄匹配的对照参与。结果指标包括与健康相关的生活质量、抑郁症状、特质焦虑、自尊、身体自我价值和六分钟步行距离。肌肉萎缩症组的生活质量评分低于对照组 ( p < .05)。在心理健康领域，抑郁症状与生活质量的相关性最大（r = -0.89，p< .001）。抑郁症状与生活质量的相关性也最大（10 个领域中的 7 个），其次是特质焦虑（10 个领域中的 6 个）、身体自我价值（10 个领域中的 5 个）、自尊（10 个领域中的 4 个）和6 分钟步行距离（10 个域中的 3 个）。心理参数以及在较小程度上影响肌肉萎缩症患者的身体机能。该研究提供了将心理评估和治疗纳入肌肉萎缩症医疗保健的基本原理。