Time varying magnetic fields (MFs) are used for the wireless power-transfer (WPT) technology. Especially, 85 kHz band MFs, which are included in the intermediate frequency (IF) band (300 Hz – 10 MHz), are commonly used WPT system for charging electric vehicles. Those applications of WPT technology have elicited public concern about health effects of IF-MF. However, existing data from health risk assessments are insufficient and additional data are needed. We assessed the genotoxic effects of IF-MF exposure on erythroid differentiation in mice. A high-intensity IF-MF mouse exposure system was constructed to induce an average whole-body electric field of 54.1 V/m. Blood samples were obtained from male mice before and after a 2-week IF-MF exposure (1 h/day, total: 10 h); X-irradiated mice were used as positive controls. We analyzed the blood samples with the micronucleus (MN) test and the Pig-a mutation assay. No significant differences were seen between IF-MF-exposed and sham-exposed mice in the frequencies of either MN or Pig-a mutations in mature erythrocytes and reticulocytes. IF-MF exposure did not induce genotoxicity in vivo under the study conditions (2.36× the basic restriction for occupational exposure, 22.9 V/m, in the International Commission on Non-Ionizing Radiation Protection (ICNIRP) guidelines). The absence of significant biological effects due to IF-MF exposure supports the practical application of this technology.

时变磁场 (MF) 用于无线电力传输 (WPT) 技术。特别是，包含在中频 (IF) 频段 (300 Hz – 10 MHz) 中的 85 kHz 频段 MF 是电动汽车充电常用的 WPT 系统。WPT 技术的这些应用引起了公众对 IF-MF 健康影响的关注。然而，来自健康风险评估的现有数据不足，需要额外的数据。我们评估了 IF-MF 暴露对小鼠红细胞分化的遗传毒性作用。构建了高强度 IF-MF 小鼠曝光系统，以诱导 54.1 V/m 的平均全身电场。在 2 周 IF-MF 暴露之前和之后（1 小时/天，总共：10 小时）从雄性小鼠中获取血液样本；X-照射的小鼠用作阳性对照。Pig-a突变测定。在成熟红细胞和网织红细胞中MN 或Pig-a突变的频率方面，在 IF-MF 暴露和假暴露小鼠之间没有发现显着差异。在研究条件下，IF-MF 暴露不会在体内诱导基因毒性（国际非电离辐射防护委员会 (ICNIRP) 指南中职业暴露基本限制的 2.36 倍，22.9 V/m）。由于 IF-MF 暴露而没有显着的生物效应支持该技术的实际应用。