Gold nanoparticles (AuNPs), produced using sodium borohydride in water (AuNPs-H), also in the presence of the surfactants cetyltrimethylammonium bromide (AuNPs-CTAB) and didecyldimethylammonium bromide (AuNPs-D10AB), were characterized and investigated in terms of their optical localized surface plasmon resonance (LSPR) response. The automation of the syntheses improved reproducibility of AuNPs. CTAB was chosen as a model one-tail surfactant capping agent for AuNPs and D10AB (two-tail surfactant) was employed for the first time, as a capping agent for AuNPs. Thus, it was possible to carry out a comparative study for the production of AuNPs, varying the surfactant concentration levels from 1.0 × 10⁻² to 1 × 10^-4 mol L^-1. The LSPR profiles were monitored in function of the time, taking into account storage conditions (at 4 °C and at 27 °C). A more unstable behavior was observed for the AuNPs produced in the presence of D10AB at 1.0 × 10^-4 mol L^-1, which suggested the disassembling of AuNPs over time. The catalytic activity of the AuNPs was evaluated in the presence of 4-nitrophenol, and the most effective kinetics were observed for systems containing the one-tail surfactant CTAB, at 1.0 × 10⁻² mol L^-1 (8 min), and for AuNPs-H, which has no organic coating, (6 min). Finally, the evaluation of the optical response from AuNPs was conducted with four aminoglycosides (AMG), indicating that these surfactants prevent interaction between AMG and the surface of the nanoparticles since at higher concentrations of CTAB or D10AB there is no significant variation in the LSPR spectral band in presence of AMG. In contrast, strong interaction, observed as variation of LSPR band, was found for the AuNPs-H-AMG systems.

还使用表面活性剂十六烷基三甲基溴化铵（AuNPs-CTAB）和二癸基二甲基溴化铵（AuNPs-D10AB）在水中使用硼氢化钠（AuNPs-H）和硼氢化钠制得的金纳米颗粒（AuNPs）进行了光学表征和研究局部表面等离子体共振（LSPR）反应。合成的自动化提高了AuNP的重现性。选择CTAB作为AuNPs的模型单尾表面活性剂封端剂，首次使用D10AB（两尾表面活性剂）作为AuNPs的封闭剂。因此，可以将表面活性剂浓度水平从1.0×10 ^-2更改为1×10 ^-4 mol L ^-1来进行AuNPs的生产的比较研究。。考虑到存储条件（在4°C和27°C下），根据时间函数对LSPR配置文件进行了监视。在D10AB的存在下，以1.0×10 ^-4 mol L ^-1产生的AuNPs观察到更不稳定的行为，这表明AuNPs随时间而分解。在4-硝基苯酚的存在下评估了AuNPs的催化活性，在1.0×10 ^-2 mol L ^-1的条件下，对于含单尾表面活性剂CTAB的体系，观察到了最有效的动力学。（8分钟），对于没有有机涂层的AuNPs-H（6分钟）。最后，使用四种氨基糖苷（AMG）对AuNPs的光学响应进行了评估，表明这些表面活性剂可防止AMG与纳米颗粒表面之间的相互作用，因为在较高浓度的CTAB或D10AB下LSPR光谱无明显变化AMG存在的乐队。相反，对于AuNPs-H-AMG系统，发现了强烈的相互作用，观察到LSPR带的变化。