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Gq-Gi-PLCβ in cells: more than the sum of its reconstituted parts
Cell Calcium ( IF 4 ) Pub Date : 2021-01-18 , DOI: 10.1016/j.ceca.2020.102340
Thomas M. Wilkie , Michael A. Hale , Sarthak Reddy

The recent paper by Pfeil et al. , “Heterotrimeric G Protein Subunit Gαq Is a Master Switch for Gβγ-Mediated Calcium Mobilization by Gi-Coupled GPCRs”, opens another path from biochemical in vitro reconstitution to understanding the complex regulation of calcium signaling inside the cell.



中文翻译:

细胞中的Gq-Gi-PLCβ:大于其重组部分的总和

Pfeil等人最近的论文。“异源三聚体G蛋白亚基Gαq是通过Gi偶联GPCR介导Gβγ介导的钙动员的主要开关”,从生化体外重建到了解细胞内钙信号的复杂调控,开辟了另一条道路。

更新日期:2021-01-19
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