Among the top five human infections requiring medical treatment is dermatitis. Treatment of bacterial and fungal skin infections is usually based on antibiotic therapy, which is often ineffective due to the involvement of antibiotic-resistant microbial strains. The aim of this study was to compare the antimicrobial activity of essential oils (EOs) and hydrolates (Hys) extracted from six aromatic plants grown in Italy (Lavandula angustifolia, Lavandula intermedia, Origanum hirtum, Satureja montana, Monarda didyma, and Monarda fistulosa) towards fungal (Candida albicans, Candida parapsilosis, Candida glabrata and Candida tropicalis; Trichophyton soudanense, Trichophyton tonsurans, Trichophyton rubrum, Trichophyton violaceum and Microsporum canis) and bacterial strains (Staphylococcus aureus MRSA, Staphylococcus aureus MSSA, Streptococcus pyogenes, E. faecalis, Enterococcus faecalis VRE, and Enterococcus faecium) potentially pathogenic for human skin. The composition and antimicrobial activity of EOs and Hys were evaluated using the Gas-chromatography mass spectrometry and micro dilution-broth test, respectively. The volatiles’ conversion factors (CFs) were calculated to compare the activity of Hys with that of the corresponding EOs. Data show that, although the minimum inhibitory concentration values of EOs are lower than the corresponding Hys, the volatiles contained in Hys are more effective at inhibiting microbial growth because they are active at lower concentrations.

中文翻译：

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氢化物的抗菌活性是否低于精油？

需要治疗的人类感染前五名之一是皮炎。细菌和真菌皮肤感染的治疗通常基于抗生素治疗，由于涉及抗生素耐药性微生物菌株，这种治疗通常无效。这项研究的目的是比较从意大利种植的六种芳香植物（薰衣草，中间薰衣草，万寿菊，Satureja montana，Monarda didyma和Monarda fistulosa）提取的六种芳香植物中提取的精油（EOs）和水合物（Hys）的抗菌活性。对真菌（白色念珠菌，副念珠菌，光滑念珠菌和热带念珠菌;苏氏毛癣菌，断发毛癣菌，红色发癣菌，紫色毛癣菌和犬小孢子菌）和细菌菌株（金黄色葡萄球菌MRSA，金黄色葡萄球菌MSSA，化脓性链球菌，粪肠球菌，粪肠球菌VRE和屎肠球菌）对人体皮肤有潜在致病性。分别使用气相色谱质谱法和微量稀释肉汤试验评估EOs和Hys的组成和抗菌活性。计算挥发物的转化因子（CF），以比较Hys的活性和相应的EO的活性。数据显示，尽管EOs的最低抑菌浓度值低于相应的Hys，但Hys中所含的挥发物由于在较低浓度下具有活性，因此在抑制微生物生长方面更有效。