The recent introduction of Pseudogymnoascus destructans (the fungal pathogen that causes white-nose syndrome in bats) from Eurasia to North America has resulted in the collapse of North American bat populations and restructured species communities. The long evolutionary history between P. destructans and bats in Eurasia makes understanding host life history essential to uncovering the ecology of P. destructans. In this Review, we combine information on pathogen and host biology to understand the patterns of P. destructans spread, seasonal transmission ecology, the pathogenesis of white-nose syndrome and the cross-scale impact from individual hosts to ecosystems. Collectively, this research highlights how early pathogen detection and quantification of host impacts has accelerated the understanding of this newly emerging infectious disease.

最近从欧亚大陆向北美引入的Pseudogymnoascus destructans（导致蝙蝠白鼻综合症的真菌病原体）导致北美蝙蝠种群的崩溃和重组的物种群落。P. destructans和欧亚大陆蝙蝠之间的长期进化史使得了解宿主生活史对于揭示P. destructans的生态学至关重要。在这篇综述中，我们结合病原体和宿主生物学的信息来了解P. destructans的模式传播、季节性传播生态学、白鼻综合征的发病机制以及个体宿主对生态系统的跨尺度影响。总的来说，这项研究强调了早期病原体检测和宿主影响的量化如何加速对这种新出现的传染病的理解。