A chemical screen identifies BET bromodomain inhibitors as inducers of an activated skin keratinocyte state that promotes the wound-healing capabilities of these cells. The study implicates epigenetic modifiers as potential targets for non-healing, chronic wounds.

中文翻译：

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加强伤口愈合

化学筛选确定BET溴结构域抑制剂是激活的皮肤角质形成细胞状态的诱导剂，可促进这些细胞的伤口愈合能力。这项研究暗示了表观遗传修饰剂可能会成为无法愈合的慢性伤口的潜在靶标。