The aim of the current study is to investigate the effect of daily long-term radio-frequency electromagnetic field (RF-EMFs) exposure on thiol/disulphide homeostasis and oxidant-antioxidant status in the serum of rats. Fourteen male Sprague Dawley rats were divided into two equal groups (n = 7). They were grouped as group 1 (sham-control) and group 2 (2100 MHz exposed). Group 2 rats were exposed to GSM-like signals for 5 h/day, 7 days per week for 14 days. In serum of blood samples, the native, total and native/total thiol levels and antioxidant-oxidant parameters were analyzed. The study revealed that the mean serum total thiol levels of GSM exposure group was rather higher than sham-control group (p = 0,219); the mean serum native thiol levels of GSM exposure group was rather higher than sham-control group (p = 0,416), and the mean serum disulphide levels of GSM exposure group was rather higher than sham-control group (p = 0,566). On the other hand, the mean serum total antioxidant status (TAS), total oxidant status (TOS) and oxidative stress index (OSI) of GSM exposure group were higher than sham-control group. There are no data in the literature, that examine the effects of RF-EMFs on thiol/disulphide homeostasis. The results of this study, indicate that RF-EMFs did not cause oxidative stress and statistically changes in thiol/disulphide homeostasis. More sample sizes and longer-term exposures are needed to confirm the results of this study.

中文翻译：

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暴露于射频电磁场后分析硫醇/二硫化物稳态和氧化-抗氧化状态


本研究的目的是研究每日长期射频电磁场（RF-EMF）暴露对大鼠血清中硫醇/二硫化物稳态和氧化-抗氧化状态的影响。将 14 只雄性 Sprague Dawley 大鼠分为相等的两个组 (n = 7)。他们被分为第 1 组（假对照组）和第 2 组（2100 MHz 暴露）。第 2 组大鼠每天接触 GSM 信号 5 小时，每周 7 天，持续 14 天。在血液样本的血清中，分析了天然、总和天然/总硫醇水平以及抗氧化剂参数。研究显示，GSM 暴露组的平均血清总硫醇水平显着高于假对照组 (p = 0,219)； GSM暴露组的平均血清天然硫醇水平显着高于假对照组(p = 0,416)，并且GSM暴露组的平均血清二硫化物水平显着高于假对照组(p = 0,566)。另一方面，GSM暴露组的平均血清总抗氧化状态（TAS）、总氧化状态（TOS）和氧化应激指数（OSI）高于假对照组。文献中没有数据检查 RF-EMF 对硫醇/二硫化物稳态的影响。这项研究的结果表明，射频电磁场不会引起氧化应激和硫醇/二硫化物稳态的统计变化。需要更多的样本量和更长期的暴露来证实这项研究的结果。