Around the world, human health and animal health are closely linked in terms of the One Health concept by ticks acting as vectors for zoonotic pathogens. Animals do not only maintain tick cycles but can either be clinically affected by the same tick-borne pathogens as humans and/or play a role as reservoirs or sentinel pathogen hosts. However, the relevance of different tick-borne diseases (TBDs) may vary in human vs. veterinary medicine, which is consequently reflected by the availability of human vs. veterinary diagnostic tests. Yet, as TBDs gain importance in both fields and rare zoonotic pathogens, such as Babesia spp., are increasingly identified as causes of human disease, a One Health approach regarding development of new diagnostic tools may lead to synergistic benefits. This review gives an overview on zoonotic protozoan, bacterial and viral tick-borne pathogens worldwide, discusses commonly used diagnostic techniques for TBDs, and compares commercial availability of diagnostic tests for humans vs. domestic animals, using Germany as an example, with the aim of highlighting existing gaps and opportunities for collaboration in a One Health framework.

在世界各地，人类健康和动物健康在“统一健康”概念中密切相关，蜱作为人畜共患病原体的载体。动物不仅维持蜱周期，而且可以在临床上受到与人类相同的蜱传播病原体的影响和/或作为宿主或前哨病原体宿主发挥作用。然而，不同蜱传疾病 (TBD) 的相关性在人类与兽医学中可能有所不同，因此人类与兽医诊断测试的可用性反映了这一点。然而，随着 TBD 在两个领域和罕见的人畜共患病原体（如巴贝虫）中的重要性增加spp.，越来越多地被确定为人类疾病的原因，关于开发新诊断工具的 One Health 方法可能会带来协同效益。这篇综述概述了世界范围内人畜共患原生动物、细菌和病毒蜱传病原体，讨论了 TBD 的常用诊断技术，并以德国为例，比较了人类与家畜诊断测试的商业可用性，目的是强调在一个健康框架中的现有差距和合作机会。