Pathological lesions as well as mucin alterations in abomasa infected by nematodes have been thoroughly studied in livestock, but such data from wild ruminants are limited or completely lacking. Pathological data for Ashworthius sidemi, an invasive nematode are particularly rare. We necropsied the abomasa of 21 wild ruminants belonging to five cervid species and detected mixed nematode infections, dominated by A. sidemi. Samples from both gross lesions and mucous membranes without macroscopically apparent pathological alterations were subjected to standard histological procedures and histochemical staining. Histological examination found chronic abomasitis, manifested by edema, and hyperemia. Various degrees of lymphoplasmacytic infiltration were observed in all samples. Initial fibrosis (8/20, 40%) was detected in samples from both gross lesions and areas without macroscopically visible changes. Tissue from hemorrhagic lesions was superficially eroded. Generalized loss of surface polysaccharides was apparent in all samples. Only residual periodic acid-Schiff and Alcian blue (pH2.5) positivity was detected in the upper abomasal pits and in mucosal neck. This study found that nematode infections, mostly by A. sidemi, caused chronic inflammation and negatively affected abomasal mucin formation in wild ruminants.

已在牲畜中彻底研究了线虫感染的阿玛沙虫中的病理性病变以及粘蛋白改变，但野生反刍动物的此类数据有限或完全缺乏。侵袭性线虫Ashworthius sidemi的病理数据特别少见。我们对属于五个鹿种的21种野生反刍动物的尸体进行了尸检，并检测到混合线虫感染，主要由A. sidemi。来自肉眼可见的病变和粘膜的样品均无肉眼可见的病理改变，并对其进行标准的组织学检查和组织化学染色。组织学检查发现慢性水肿，表现为水肿和充血。在所有样品中均观察到不同程度的淋巴浆细胞浸润。在肉眼可见的病变和无肉眼可见变化的区域的样本中均检测到初始纤维化（8 / 20，40％）。出血性病变的组织被表面侵蚀。在所有样品中表面多糖的普遍损失是明显的。在上颌骨坑和粘膜颈部仅检测到残留的高碘酸-席夫氏和阿尔辛蓝（pH2.5）阳性。这项研究发现线虫感染主要是由A. sidemi引起慢性发炎，并在野生反刍动物中负面影响肉芽肿粘蛋白的形成。