Single giant unilamellar vesicles (GUVs) rupture spontaneously from their salt-laden suspension onto solid surfaces. At hydrophobic surfaces, the GUVs rupture via a recurrent, bouncing ball rhythm. During each contact, the GUVs, rendered tense by the substrate interactions, porate and spread a molecularly transformed motif of a monomolecular layer on the hydrophobic surface from the point of contact in a symmetric manner. The competition from pore closure however limits the spreading and produces a daughter vesicle, which re-engages with the substrate. At solid hydrophilic surfaces, by contrast, GUVs rupture via a distinctly different recurrent burst-heal dynamics: during burst, single pores nucleate at the contact boundary of the adhering vesicles facilitating asymmetric spreading and producing a "heart" shaped membrane patch. During the healing phase, the competing pore closure produces a daughter vesicle. In both cases, the pattern of burst-reseal events repeats multiple times splashing and spreading the vesicular fragments as bilayer patches at the solid surface in a pulsatory manner. These remarkable recurrent dynamics arise not because of the elastic properties of the solid surface but because the competition between membrane spreading and pore healing, prompted by the surface-energy dependent adhesion, determine the course of the topological transition.

中文翻译：

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固体表面巨型脂质囊泡破裂转变的循环动力学

单个巨大的单层囊泡 (GUV) 从它们的含盐悬浮液中自发破裂到固体表面上。在疏水表面，GUV 会通过反复的弹跳球节奏破裂。在每次接触期间，由于底物相互作用而变得紧张的 GUV 从接触点以对称方式在疏水表面上穿孔并散布单分子层的分子转化基序。然而，来自孔隙闭合的竞争限制了扩散并产生子囊泡，该囊泡重新与基质接合。相比之下，在固体亲水表面上，GUV 通过明显不同的反复爆发愈合动力学破裂：在爆发期间，单个孔在粘附囊泡的接触边界处成核，促进不对称扩散并产生“心”形膜贴片。在愈合阶段，竞争性毛孔闭合产生子囊泡。在这两种情况下，爆发-重新密封事件的模式重复多次，以脉动方式在固体表面以双层斑块形式溅射和散布水泡碎片。这些显着的循环动力学的出现不是因为固体表面的弹性特性，而是因为膜扩散和孔愈合之间的竞争，由表面能依赖性粘附引起，决定了拓扑转变的过程。