We performed a complex morphological study of biopsy samples of prostate gland from 30 men (mean age 46±11 years) with chronic abacterial prostatitis who were exposed unfavorable anthropogenic factors. The ultrastructural heterogeneity of smooth muscle cells was shown, among which cells with destructive changes in organelles predominated, solitary cells with signs of secretory function were revealed. Most endothelial cells in microvessels were characterized by low pinocytotic activity, destruction of organelles; focal hyperplastic ultrastructural changes were noted in some endotheliocytes. Along with fibroblasts, the stroma contained single mast cells; no inflammatory infiltration was revealed. The results of the study attested to complex mechanisms of remodeling of the prostate gland stroma in chronic abacterial prostatitis involving microvessels, smooth muscle cells, and probably mast cells, which determines the development of degenerative, destructive, and fibrotic processes.

中文翻译：

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慢性细菌性前列腺炎前列腺基质重塑的特点

我们对 30 名患有慢性细菌性前列腺炎的男性（平均年龄 46±11 岁）的前列腺活检样本进行了复杂的形态学研究，这些男性暴露于不利的人为因素。显示了平滑肌细胞的超微结构异质性，其中细胞器破坏性变化的细胞占主导地位，揭示了具有分泌功能迹象的孤立细胞。大多数微血管内皮细胞的特点是胞饮活性低，细胞器破坏；在一些内皮细胞中观察到局灶性增生超微结构变化。与成纤维细胞一起，基质含有单个肥大细胞；未发现炎症浸润。研究结果证明了涉及微血管的慢性细菌性前列腺炎中前列腺基质重塑的复杂机制，