The analysis of ancient proteins from paleontological, archeological, and historic materials is revealing insights into past subsistence practices, patterns of health and disease, evolution and phylogeny, and past environments. This review tracks the development of this field, discusses some of the major methodological strategies used, and synthesizes recent developments in archeological applications of ancient protein analysis. Moreover, this review highlights some of the challenges faced by the field and potential future directions, arguing that the development of minimally invasive or nondestructive techniques, strategies for protein authentication, and the integration of ancient protein analysis with other biomolecular techniques are important research strategies as this field grows.

对来自古生物学、考古学和历史材料的古代蛋白质的分析揭示了对过去生存实践、健康和疾病模式、进化和系统发育以及过去环境的见解。这篇综述追踪了该领域的发展，讨论了一些主要的方法策略，并综合了古代蛋白质分析考古应用的最新进展。此外，本综述强调了该领域面临的一些挑战和潜在的未来方向，认为微创或无损技术的发展、蛋白质鉴定策略以及古代蛋白质分析与其他生物分子技术的整合是重要的研究策略，因为这个领域增长。