More than a decade ago, Embi and Payne¹ proposed a definition of clinical research informatics as “the subdomain of biomedical informatics concerned with the development, application, and evaluation of theories, methods, and systems to optimize the design and conduct of clinical research and the analysis, interpretation, and dissemination of the information generated.” Three years later, a Journal of the American Medical Informatics Association (JAMIA) supplement on clinical research informatics was published. This included an article by Kahn and Weng² that presented a conceptual model that was used to highlight 18 articles in the issue. In 2018, JAMIA Editor-in-Chief Lucila Ohno-Machado highlighted multiple clinical research informatics articles and predicted the growth of clinical research informatics as a subspecialization in biomedical informatics.³ Five articles in this first issue of 2021,^4–8 and many more in the 2019 and 2020 volumes of JAMIA, support the accuracy of Ohno-Machado’s prediction.

中文翻译：

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临床研究信息学作为生物医学信息学子领域的成熟

十多年前，Embi 和 Payne ¹提出临床研究信息学的定义为“生物医学信息学的一个子领域，涉及理论、方法和系统的开发、应用和评估，以优化临床研究的设计和实施以及对生成的信息进行分析、解释和传播。” 三年后，美国医学信息学协会( JAMIA ) 杂志发表了一份关于临床研究信息学的增刊。其中包括 Kahn 和 Weng ²的一篇文章，该文章提出了一个概念模型，该模型用于突出该问题中的 18 篇文章。2018 年，JAMIA主编 Lucila Ohno-Machado 强调了多篇临床研究信息学文章，并预测临床研究信息学作为生物医学信息学的一个子专业的发展。³ JAMIA 2019 年和 2020 年第一期中的 5 篇文章、^4-8篇以及更多文章，支持 Ohno-Machado 预测的准确性。