Patients with diabetes are considered a high-risk group involved with cerebral mucormycosis (CM). Due to the potential of Mucorales to invade sinuses and its rapid progression into orbit and retro-orbital areas and even brain, in most cases, CM is fatal in patients with diabetes. In the last few decades, mucormycosis and background conditions responsible for the development of its infections have received a great deal of attention. Dysfunction of innate and adaptive immune system, the increased amount of available nutrition, expression of host factors, and free iron level in plasma in diabetic ketoacidosis are among the topics that have been mostly taken into account so far. Therefore, it is important to clarify the molecular mechanisms that let the Mucorales to involve the patients with diabetes, which even at early stages of diagnosis and treatment, there is minimum chance to control the disease.

中文翻译：

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仔细研究糖尿病患者脑毛霉菌病的发病机制：一个小综述

糖尿病患者被认为是脑毛霉菌病 (CM) 的高危人群。由于毛霉菌有可能侵入鼻窦并迅速进入眼眶和眶后区域甚至大脑，因此在大多数情况下，CM 对糖尿病患者是致命的。在过去的几十年里，毛霉菌病和导致其感染发展的背景条件受到了极大的关注。先天性和适应性免疫系统功能障碍、可用营养量的增加、宿主因子的表达以及糖尿病酮症酸中毒血浆中的游离铁水平是迄今为止最受关注的话题。因此，阐明毛囊藻参与糖尿病患者的分子机制非常重要，