In the present work, the exceptional electrochemical properties of carbon paper were characterized and explored in the development of a sensor for the anti-inflammatory drug, ketoprofen. An initial electrochemical characterization of the carbon paper with a redox indicator revealed much higher voltammetric peaks in comparison with other carbon-based electrodes, namely, screen-printed carbon electrode, boron-doped diamond electrode, glassy carbon electrode, pyrolytic graphite electrode, and pencil graphite electrode, predicting a good sensing performance. Ketoprofen showed a pronounced cathodic peak around −1.1 V vs Ag/AgCl (KCl, 3 M) at pH 5 in Britton-Robinson buffer, presenting a diffusion-controlled process. An optimized differential pulse voltammetry procedure was employed for ketoprofen determination achieving a limit of detection of 0.11 ± 0.01 μM, a linearity up to 6.02 μM, and a high sensitivity of 24 ± 4 or 35 ± 3 μA μM⁻¹ cm⁻² (depending on the calibration range: 0.088–1.96 μM or 1.96–6.02 μM, respectively) with acceptable (6–15% relative standard deviation) reproducibility and repeatability considering the challenging conditions of its detection in aqueous solutions. The sensor revealed to be highly selective in the presence of common interferents and other widely consumed anti-inflammatory drugs. Moreover, the developed sensor reached good accuracy in wastewater and fish samples with recoveries varying from 82.3 ± 4.4 to 88.6 ± 4.5%.

在目前的工作中，在开发消炎药酮洛芬传感器的过程中，对炭纸的卓越电化学性能进行了表征和探索。与其他碳基电极（丝网印刷碳电极，掺硼金刚石电极，玻璃碳电极，热解石墨电极和铅笔）相比，具有氧化还原指示剂的碳纸的初始电化学表征显示出更高的伏安峰。石墨电极，预示着良好的传感性能。酮洛芬在pH值为5的Britton-Robinson缓冲液中，相对于Ag / AgCl（KCl，3 M）在-1.1 V附近显示明显的阴极峰，表现出扩散受控的过程。优化的差分脉冲伏安法用于酮洛芬的测定，检测极限为0.11±0。^-1  cm ^-2（取决于校准范围：分别为0.088–1.96μM或1.96–6.02μM），考虑到在水溶液中检测的挑战性条件，其可重复性和可重复性（可接受的相对标准偏差为6–15％）。该传感器在常见干扰物和其他广泛使用的抗炎药的存在下具有高度选择性。而且，开发的传感器在废水和鱼类样品中具有很高的精度，回收率从82.3±4.4到88.6±4.5％不等。