In this study, an efficient hybrid nanocatalyst made of guar gum (guarana, as a natural basis), magnetic iron oxide nanoparticles, and copper(I) oxide nanoparticles (Cu₂O NPs) is fabricated and suitably applied for catalyzing the multicomponent (three- and four-component) synthesis reactions of imidazole derivatives. Here, an easy preparation strategy for this novel catalytic system (Cu₂O/Fe₃O₄@guarana) is presented. Then, the application of this catalytic system for the synthesis of imidazole derivatives is precisely investigated. For this purpose, ultrasonication is introduced as an efficient and fast method. In summary, the high catalytic efficiency of Cu₂O/Fe₃O₄@guarana nanocomposite is well demonstrated by high reaction yields obtained in the presence of a small amount of this nanocomposite, under mild conditions. Wide active surface area, substantial magnetic behavior, excellent heterogeneity, suitable stability, well reusability, and etc. have distinguished this catalytic system as an instrumental tool for facilitating the complex synthetic reactions.

在这项研究中，由瓜尔胶（瓜尔那胶，作为自然基础），磁性氧化铁纳米颗粒和氧化铜（I）纳米颗粒（Cu ₂ O NPs）制成的高效杂化纳米催化剂被制备并适用于催化多组分（三种）。 -和四组分）咪唑衍生物的合成反应。在这里，提出了一种简便的制备策略，用于这种新型的催化体系（Cu ₂ O / Fe ₃ O ₄ @瓜拉那）。然后，精确研究了该催化体系在合成咪唑衍生物中的应用。为此目的，引入超声波处理是一种有效且快速的方法。综上所述，Cu ₂ O / Fe ₃ O ₄的高催化效率通过在温和条件下在少量这种纳米复合材料的存在下获得的高反应产率，很好地证明了瓜拉纳纳米复合材料。宽的活性表面积，显着的磁性，出色的异质性，合适的稳定性，良好的可重复使用性等，已使该催化体系成为促进复杂合成反应的工具。