The widespread occurrence of persistent organic pollutants (POPs) in the environment is a matter of concern. In this study, selected organohalogenated contaminants, including dichlorodiphenyltrichloroethane and its metabolites (DDTs) polychlorinated biphenyls (PCBs), chlordanes (CHLs), hexachlorobenzene (HCB), polybrominated diphenyl ethers (PBDEs), hexabromocyclododecanes (HBCDs), tetrabromobisphenol A (TBBPA), 2,4,6-tribromophenol (TBP), were measured in complete meal sets (24-h duplicate-diet) of Japanese infants to investigate the levels, profiles, and possible sources of contamination. In total, 46 whole-day meals of infants (7–24-months old) were collected during 2017 from Fukuoka, Japan. To the best of our knowledge, this is the first report based on the duplicate-diet method for infants. The median intakes among the POP groups were highest for ΣDDTs (18 ng/day, maximum 251 ng/day), followed by ΣPCBs (17 ng/day, maximum 198 ng/day), ΣCHLs (14 ng/day, maximum 105 ng/day), HCB (11 ng/day, maximum 64 ng/day), TBP (3.5 ng/day, maximum 109 ng/day), ΣHBCDs (1.9 ng/day, maximum 70 ng/day), TBBPA (0.72 ng/day, maximum 34 ng/day), and ΣPBDEs (0.11 ng/day, maximum 4.5 ng/day). Among the PCBs, PCB-138 and PCB-153 were the most abundant congeners (27% and 23%, respectively). p,p’-DDE, the major DDT metabolite, accounted for 96% of total DDTs. Among PBDEs, BDE47 was the only detected congener (present in 4% of the samples). The dietary intake of the targeted compounds was lower than the intake via breast milk, suggesting that the exposure from baby food was limited. In the principal component analysis, chlorinated and brominated compounds were separated on principal component 1, while TBP and α-HBCD were separated on principal component 2, likely suggesting a differing emission time trend or source. PCB-153, PCB-138, trans-chlordane, cis-chlordane, and trans-nonachlor were correlated with seafood consumption (Spearman's ρ = 0.45 to 0.57, p < 0.05), while TBP was correlated with seaweed consumption (Spearman's ρ = 0.46, p < 0.05). Also, four species of commercial edible seaweed in Japan were analyzed to confirm the findings of the duplicate-diet study. The relatively high concentration of TBP (5.5 ± 6.6 ng/g wet weight) was observed in the seaweed samples, indicating that seaweed is a potential exposure source of TBP.

环境中广泛存在的持久性有机污染物（POPs）是一个令人关注的问题。在这项研究中，选定的有机卤代污染物包括二氯二苯基三氯乙烷及其代谢物（DDT），多氯联苯（PCB），氯丹（CHL），六氯苯（HCB），多溴二苯醚（PBDE），六溴环十二烷（HBCD），四溴双酚A（TB）在日本婴儿的全餐（24小时重复饮食）中测量了2,4,6-三溴苯酚（TBP），以研究其水平，概况和可能的污染源。2017年，日本福冈市共收集了46份全日制婴儿餐（7-24个月大）。据我们所知，这是第一份基于重复饮食方法的婴儿报告。POP组中的摄入量中位数最高的是ΣDDT（18 ng /天，最大251 ng /天），其次是ΣPCBs（17 ng /天，最大198 ng /天），ΣCHL（14 ng /天，最大105 ng）。 /天），六氯苯（11 ng /天，最大64 ng /天），TBP（3.5 ng /天，最大109 ng /天），ΣHBCD（1.9 ng /天，最大70 ng /天），TBBPA（0.72 ng /天） /天，最大34 ng /天）和ΣPBDEs（0.11 ng /天，最大4.5 ng /天）。在PCB中，PCB-138和PCB-153是最丰富的同类产品（分别为27％和23％）。p，p'-DDE是DDT的主要代谢产物，占DDT总量的96％。在多溴二苯醚中，BDE47是唯一检测到的同类物（在4％的样品中存在）。目标化合物的饮食摄入量低于母乳摄入量，这表明婴儿食品的摄入量受到限制。在主成分分析中，氯和溴化化合物在主成分1上分离，而TBP和α-六溴环十二烷在主成分2上分离，这可能表明排放时间趋势或来源不同。PCB-153，PCB-138，反式氯丹，顺式氯丹和反式九氯与海鲜消费量相关（Spearmanρ= 0.45至0.57，p <0.05），而TBP与海藻的食用量相关（Spearmanρ= 0.46） ，p ＜0.05）。还，对日本的四种商品食用海藻进行了分析，以证实重复饮食研究的结果。在海藻样品中观察到相对较高的TBP浓度（5.5±6.6 ng / g湿重），表明海藻是TBP的潜在暴露源。