A Schiff base ligand named bis(5-bromo-2-hydroxybenzaldehyde) 1,2-propanediimine has been used to fabricate a modified glassy carbon electrode for the selective voltammetric detection of the low-level of Cu(II). The electrochemical behavior of unmodified and modified electrodes was investigated using the cyclic voltammetry technique, while the optimization of the parameters affecting the electrode characteristics and its analytical performance were evaluated by employing the differential pulse anodic stripping voltammetry. Under the optimized conditions (pH 4, decomposition time 360 s, decomposition potential vs. SCE − 1.2 V), the peak current variation as a function of the copper(II) concentration in the range of 10–100 nM was linear, with a calculated detection limit of 4.2 nM. The evaluated selectivity, reproducibility, and repeatability of the developed modified electrode showed its satisfactory performance. The ability of the prepared electrode was evaluated by its application for the analysis of Cu(II) in a fish liver tissue sample. It was confirmed also that the proposed modifie delectrode can be successfuly used for the determination of Cd(II) and Pb(II).

Graphic abstract

中文翻译：

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使用席夫碱改性玻碳工作电极伏安法测定痕量铜（II），镉（II）和铅（II）

席夫碱配体名为双（5-溴-2-羟基苯甲醛）1,2-丙二胺已被用于制备修饰的玻碳电极，用于选择性伏安法检测低含量的Cu（II）。使用循环伏安法研究了未修饰和修饰电极的电化学行为，同时采用差分脉冲阳极溶出伏安法评估了影响电极特性的参数及其分析性能的优化。在最佳条件下（pH 4，分解时间360 s，分解电势与SCE-1.2 V），在10–100 nM范围内，峰值电流随铜（II）浓度的变化呈线性关系，计算的检出限为4.2 nM。评估的选择性，可重复性，所开发的修饰电极的重复性显示出令人满意的性能。通过将其用于鱼肝组织样品中Cu（II）的分析来评估所制备电极的能力。还证实了所提出的修饰的电极可以成功地用于测定Cd（II）和Pb（II）。

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